ENZYMATIC TRANSAMINATION REACTIONS INVOLVING ARGININE AND ORNITHINE
نویسندگان
چکیده
منابع مشابه
Enzymatic transamination reactions involving arginine and ornithine.
Recent research has resulted in considerable modification of the earlier concept that enzymatic transamination was limited to reactions between alanine, aspartate, glutamate, and their or-keto analogues. Reactions leading to the reversible amination of the cY-keto analogues of many of the natural amino acids have been described (l-5), and there is also evidence that aldehyde groups may particip...
متن کاملArginine racemase of Pseudomonas graveolens. II. Racemization and transamination of ornithine catalyzed by arginine racemase.
Arginine racemase from Pseudomonas graveolens is inactivated by preliminary incubation with Lor D-ornithine, 6-Nacetyl-L-ornithine, and L-2,4-diaminobutyrate at pH 10.0. Loss of the enzyme activity is associated with formation of a new spectrum with an absorption maximum in the region of 320 rnp and disappearance of a peak at 420 mp. The inactivation is prevented, and the inactivated enzyme is ...
متن کاملThe stereochemistry of enzymatic transamination.
An approach to the determination of the complete stereochemistry of enzymatic transamination is described. Stereospecificity in the enzymatic labilization of one of the 4-methylene protons of pyridoxamine has been demonstrated in the transamination of pyridoxamine catalyzed by apoglutamate-oxaloacetate transaminase. Both enantiomers of the 4-(CHD-NH2) pyridoxamine have been prepared. These comp...
متن کامل5 Arginine , Citrulline , and Ornithine
Metabolism as well as function of the three amino acids, L-arginine, L-citrulline, and Lornithine, are closely intertwined and related to the homeostasis of nitric oxide at the tissue and cellular levels. For the three compounds data on neural tissue and CSF levels are summarized and localization in brain mainly derived from immunohistochemical experiments is reported. A complex pattern of diff...
متن کاملCan arginine and ornithine support gut functions?
Arginine and ornithine are precursors of nitric oxide and polyamines, respectively. These metabolites intimately participate in permeability and adaptive responses of the gut. The liver possesses high arginase activity as an intrinsic part of urea synthesis and would consume most of the portal supply of dietary arginine. The gut reduces this possibility by converting dietary arginine to citrull...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1954
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)50826-2